Addiction directly affects roughly 25 million Americans and indirectly affects an additional 40 million (1). About 16 million Americans suffer from alcoholism and 21.6 million are addicted to drugs. The current opioid crisis affects 1.7 million people in the United States. Between 21 and 29% of patients prescribed opioids for chronic pain misuse them. Addiction is a disease that can be indicative of further mental health conditions. Treatments can include support networks, detoxes, and residential treatments. 

1. CBD as an Intervention for Addictive Behaviors
2. CBD reduces cigarette consumption in tobacco smokers
3. Inhibition of monoacylglycerol lipase enzyme reduces nicotine withdrawal
4. CBD inhibits the reward-facilitating effect of morphine
5. Cannabidiol, a non-psychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances
6. Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats
7. Impact of Cannabis Use during Stabilization on Methadone Maintenance Treatment
8. Medical cannabis laws and opioid analgesic overdose mortality in the United States, 1999-2010
9. Dysregulation of cannabinoid CB1 receptor and associated signaling networks in brains of cocaine addicts and cocaine-treated rodents
10. Comparison of CBD, antioxidants, and diuretics in reversing binge ethanol-induced neurotoxicity
11. Transdermal delivery of CBD attenuates binge alcohol-induced neurodegeneration in a rodent model of an alcohol use disorder
12. CBD for the treatment of cannabis withdrawal syndrome
13. Cannabis use disorders are comparatively prevalent among nonwhite racial/ethnic groups and adolescents
14. CBD Counteracts Amphetamine-Induced Neuronal and Behavioral Sensitization of the Mesolimbic Dopamine Pathway
15. CBD regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders
16. Early Phase in the Development of CBD as a Treatment for Addiction: Opioid Relapse Takes Initial Center Stage
17. Drug Memories: CBD and Addiction
18. America’s opiate crisis: How medical cannabis can help
19. Is Kratom the CBD of opioids?
20. Survey: Cannabis better than big pharma meds for PTSD
21. Marijuana use does not cause brain abnormalities
22. Of course marijuana addiction exists. And it’s (almost) all in your head.
23. Alcoholism and the endocannabinoid system
24. CBD versus Nicotine
25. Epigenetic mechanisms associated with addiction-related behavioural effects of nicotine and/or cocaine: implication of the endocannabinoid system
26. Effects of Cannabidiol on Morphine Conditioned Place Preference in Mice